Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids
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چکیده
منابع مشابه
Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids.
TLF (TBP-like factor) is a protein commonly thought to belong to the general transcription initiation complex. TLF is evolutionarily conserved and has been shown to be essential for early development in C. elegans, zebrafish and Xenopus. In mammals however, TLF has a specialised function, as revealed by targeted mutation of the gene in the mouse germline. The TLF mutation elicits a complete arr...
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ژورنال
عنوان ژورنال: Development
سال: 2002
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.129.4.945